死亡相关转录因子1抗体简介说明

英文名称    DATF1    

中文名称    死亡相关转录因子1抗体    

别    名    BYE 1; BYE1; C20orf158; DATF 1; Death associated transcription factor 1; Death inducer obliterator 1; DIDO 1; DIDO 2; DIDO 3; DIDO1; DIDO2; DIDO3; DIO 1; DIO1; hDido 1; hDido1; KIAA0333; DIDO1_HUMAN.    

供 应 商    远慕生物

研究领域    细胞生物  细胞凋亡  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,     

产品应用    ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）死亡相关转录因子1抗体 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    244kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DATF1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

死亡相关转录因子1抗体产品介绍    background:

Apoptosis plays an important role in many cellular processes. In mice, the death inducer obliterator 1 (Dio1) gene, a putative transcription factor, is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. Dio1 expression is upregulated when an apoptosis is detected. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. Human DATF1 (death associated transcription factor 1) is similar to the mouse gene and therefore is thought to be involved in apoptosis.

Function:
Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the indoleamine 2,3-dioxygenase family.

Database links:
UniProtKB/Swiss-Prot: Q9BTC0.5

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.