延伸因子EF-1 γ抗体实验介绍

中文名称    延伸因子EF-1 γ抗体    

英文名称    EEF1G

别    名    2610301D06Rik; AA407312; eEF 1B gamma; EEF 1G; eEF-1B gamma; EEF1G; EF 1 gamma; EF 1G; EF-1-gamma; EF1 gamma; EF1G; EF1G_HUMAN; Elongation factor 1 gamma; Elongation factor 1-gamma; Eukaryotic translation elongation factor 1 gamma; GIG 35; GIG35; MGC103354; MGC114210; MGC144723; MGC144724; MGC94929; Pancreatic tumor related protein; PRO1608; Translation elongation factor eEF 1 gamma chain.    

供 应 商    远慕生物      

研究领域    细胞生物  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 延伸因子EF-1 γ抗体（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    50kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EEF1G    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

延伸因子EF-1 γ抗体产品介绍    background:

EF-1 (elongation factor-1) is a multi-protein complex that is responsible for the delivery of aminoacyl-tRNAs to the ribosome. EF-1 gamma (elongation factor 1-gamma), also known as EEF1G or GIG35, is a 437 amino acid subunit of the EF-1 complex. Expressed in stomach, pancreas, brain, lung, kidney, intestine, liver and spleen, EF-1 gamma contains an N-terminal glutathione transferase domain which is thought to be involved in anchoring the complex to various cellular components. Additionally, EF-1 gamma may play a key role in the assembly of multiprotein complexes containing aminoacyl-tRNA synthetases. Increased expression of EF-1 gamma is associated with pancreatic cancer, suggesting a possible role for EF-1 gamma in the oncogenic transformation process.

Function:
Probably plays a role in anchoring the complex to other cellular components.

Subunit:
EF-1 is composed of four subunits: alpha, beta, delta, and gamma.

Tissue Specificity:
Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.

Similarity:
Contains 1 EF-1-gamma C-terminal domain.
Contains 1 GST C-terminal domain.
Contains 1 GST N-terminal domain.

Database links:
UniProtKB/Swiss-Prot: P26641.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.